Does Size Matter?

I record my dj mixes to my hard drive in .wav format, and until now, the mixes that I've uploaded and shared on this blog are compressed and re-encoded at a constant bitrate of 160Kbps. The only reason I compress to this bitrate is to keep the filesize under the share sites' 100Mb maximum. So, in the interest of sound quality, I'm uploading my next few mixes encoded at 320Kbps. I welcome any feedback, be it regarding sound quality, file size, whether you love it or hate it or if you really couldn't care less. I may also share some future goodies uploaded at high and not so high compression rates.